BDBM329750 Preparation of 2-[6-(4-chlorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1]-benzazepin-4-yl]-1-(morpholin-4-yl)ethanone::US9663523, Example 14

SMILES Cc1nnc2C(CC(=O)N3CCOCC3)C=C(c3ccc(Cl)cc3)c3ccccc3-n12

InChI Key InChIKey=GCMMHCYQCBJPDX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 329750   

TargetBromodomain-containing protein 4(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329750(US9663523, Example 14 | Preparation of 2-[6-(4-chl...)
Affinity DataIC50: 310nMAssay Description:For this purpose, a time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used, which measures the binding between N-terminally Hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent