BDBM329756 Preparation of 2-[6-(4-chlorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1]benzazepin-4-yl]-N-(2-oxo-2,3-dihydro-1H-indol-5-yl)acetamide::US9663523, Example 20

SMILES Cc1nnc2C(CC(=O)Nc3ccc4NC(=O)Cc4c3)C=C(c3ccc(Cl)cc3)c3ccccc3-n12

InChI Key InChIKey=HQHXROQNFTYBRD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 329756   

TargetBromodomain-containing protein 4(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329756(Preparation of 2-[6-(4-chlorophenyl)-1-methyl-4H-[...)
Affinity DataIC50:  240nMAssay Description:For this purpose, a time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used, which measures the binding between N-terminally Hi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent