BDBM329791 Preparation of 2-{[(4R)-6-(4-chlorophenyl)-1-methyl-8-(trifluoromethoxy)-4H-[1,2,4]triazolo[4,3-a][1]benzazepin-4-yl]acetyl}hexahydropyrrolo[1,2-a]pyrazin-6(2H)-one::US9663523, Example 56

SMILES Cc1nnc2[C@H](CC(=O)N3CCN4C(CCC4=O)C3)C=C(c3ccc(Cl)cc3)c3cc(OC(F)(F)F)ccc3-n12

InChI Key InChIKey=ZLMFFCGXKCSHMI-LROBGIAVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 329791   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329791(Preparation of 2-{[(4R)-6-(4-chlorophenyl)-1-methy...)
Affinity DataIC50:  180nMAssay Description:For this purpose, a time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used, which measures the binding between N-terminally Hi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent