BDBM330296 (S)-methyl (5-(4-(3-methylmorpholino)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)pyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-(trifluoromethyl)pyridin-2-yl)carbamate::US9724352, I-35

SMILES COC(=O)Nc1cc(c(cn1)-c1nc(N2CCOC[C@@H]2C)c2cc(CN3CCN(CC3)S(C)(=O)=O)cn2n1)C(F)(F)F

InChI Key InChIKey=XBULAPXCKGKHCL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 330296   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM330296(US9724352, I-35 | (S)-methyl (5-(4-(3-methylmorpho...)
Affinity DataIC50: 5.67nMAssay Description:The activity of purified kinase was detected with Kinase-Glo Plus kinase luminescent assay by measuring the amount of the remaining Kinase in the sol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent