BDBM330362 2-(4-Fluoro-3-{[(3R,6R)- 6-methyl-1-{[2-(2H- 1,2,3-triazol-2-yl) phenyl]carbonyl} piperidin-3-yl] oxy}phenyl) propan-2-ol::US9725434, 20

SMILES C[C@@H]1CC[C@H](CN1C(=O)c1ccccc1-n1nccn1)Oc1cc(ccc1F)C(C)(C)O

InChI Key InChIKey=NJKWDLFCTNYMNN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330362   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM330362(US9725434, 20 | 2-(4-Fluoro-3-{[(3R,6R)- 6-methyl-...)
Affinity DataIC50: 354nMAssay Description:The following table shows representative data for the compounds of the Examples as orexin receptor antagonists as determined by the FLIPR Ca2+ Flux A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM330362(US9725434, 20 | 2-(4-Fluoro-3-{[(3R,6R)- 6-methyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:The following table shows representative data for the compounds of the Examples as orexin receptor antagonists as determined by the FLIPR Ca2+ Flux A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent