BDBM330369 (1S)-6-{[(3R,6R)- 6-Methyl-1-{[2- (2H-1,2,3-triazol- 2-yl)phenyl] carbonyl} piperidin-3-yl]oxy}-2,3-dihydro-1H-inden-1-ol::US9725434, 28

SMILES C[C@@H]1CC[C@H](CN1C(=O)c1ccccc1-n1nccn1)Oc1ccc2CC[C@H](O)c2c1

InChI Key InChIKey=JQYXDTJYVYRKOX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330369   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM330369(US9725434, 28 | (1S)-6-{[(3R,6R)- 6-Methyl-1-{[2- ...)
Affinity DataIC50: 394nMAssay Description:The following table shows representative data for the compounds of the Examples as orexin receptor antagonists as determined by the FLIPR Ca2+ Flux A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM330369(US9725434, 28 | (1S)-6-{[(3R,6R)- 6-Methyl-1-{[2- ...)
Affinity DataIC50: 1.00E+4nMAssay Description:The following table shows representative data for the compounds of the Examples as orexin receptor antagonists as determined by the FLIPR Ca2+ Flux A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent