BDBM330373 (1S)-1-Methyl-4- {[(3R,6R)-6-methyl- 1-{[2-(2H-1,2,3- triazol-2-yl) phenyl]carbonyl} piperidin-3-yl] oxy}-2,3-dihydro- 1H-inden-1-ol::US9725434, 32

SMILES C[C@@H]1CC[C@H](CN1C(=O)c1ccccc1-n1nccn1)Oc1cccc2c1CC[C@]2(C)O

InChI Key InChIKey=WBQYWJZWQICDEX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330373   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM330373(US9725434, 32 | (1S)-1-Methyl-4- {[(3R,6R)-6-methy...)
Affinity DataIC50: 34nMAssay Description:The following table shows representative data for the compounds of the Examples as orexin receptor antagonists as determined by the FLIPR Ca2+ Flux A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM330373(US9725434, 32 | (1S)-1-Methyl-4- {[(3R,6R)-6-methy...)
Affinity DataIC50: 648nMAssay Description:The following table shows representative data for the compounds of the Examples as orexin receptor antagonists as determined by the FLIPR Ca2+ Flux A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent