BDBM330376 (1R)-1-Methyl-6- {[(3R,6R)-6- methyl-1-{[2- (2H-1,2,3- triazol-2-yl) phenyl]carbonyl}piperidin-3-yl]oxy}-2,3-dihydro-1H-inden-1-ol::US9725434, 34

SMILES C[C@@H]1CC[C@H](CN1C(=O)c1ccccc1-n1nccn1)Oc1ccc2CC[C@@](C)(O)c2c1

InChI Key InChIKey=KMGDOUIRHLBSDF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330376   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM330376(US9725434, 34 | (1R)-1-Methyl-6- {[(3R,6R)-6- meth...)
Affinity DataIC50: 112nMAssay Description:The following table shows representative data for the compounds of the Examples as orexin receptor antagonists as determined by the FLIPR Ca2+ Flux A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM330376(US9725434, 34 | (1R)-1-Methyl-6- {[(3R,6R)-6- meth...)
Affinity DataIC50: 1.17E+3nMAssay Description:The following table shows representative data for the compounds of the Examples as orexin receptor antagonists as determined by the FLIPR Ca2+ Flux A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent