BDBM330387 US9725435, 32

SMILES CC(=O)c1ccc(NC(=O)C2N(CCc3ccc(C)cc23)C(=O)\C=C\c2cc(Cl)ccc2-n2cnnn2)cc1

InChI Key InChIKey=JLLCYJRNFDBRCR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 330387   

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM330387(US9725435, 32)
Affinity DataKi:  5.12E+3nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent