BDBM330803 (S)-1,1,1,3,3,3-hexafluoro-2-(2-((1-((4-fluorobenzyl)-1H-pyrazol-5-yl)methyl)-1-((4-fluorophenyl)sulfonyl)-1,2,3,4-tetrahydroquinolin-6-yl)propan-2-ol::US9725443, 16

SMILES OC(c1ccc2N([C@H](Cc3ccnn3Cc3ccc(F)cc3)CCc2c1)S(=O)(=O)c1ccc(F)cc1)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=WPOUYVFYBNAPSI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 330803   

TargetNuclear receptor ROR-gamma(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM330803((S)-1,1,1,3,3,3-hexafluoro-2-(2-((1-((4-fluorobenz...)
Affinity DataIC50: 192nMAssay Description:The binding of potential ligands to RORγ is measured by competition with [3H] 25-hydroxycholesterol using a scintillation proximity assay (SPA) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent