BDBM330807 (S)-benzyl 2-(5-((1-((4-fluorophenyl)sulfonyl)-6-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,2,3,4-tetrahydroquinolin-2-yl)methyl)-1,3,4-oxadiazol-2-yl)acetate::US9725443, 20

SMILES OC(c1ccc2N([C@H](Cc3nnc(CC(=O)OCc4ccccc4)o3)CCc2c1)S(=O)(=O)c1ccc(F)cc1)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=ASRSSNZXTVVSLU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 330807   

TargetNuclear receptor ROR-gamma(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM330807((S)-benzyl 2-(5-((1-((4-fluorophenyl)sulfonyl)-6-(...)
Affinity DataIC50: 122nMAssay Description:The binding of potential ligands to RORγ is measured by competition with [3H] 25-hydroxycholesterol using a scintillation proximity assay (SPA) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent