BDBM331157 1-(1H-pyrrolo[2,3-b]pyridin-3-yl)-2,6-naphthyridine::US9725446, Compound A16

SMILES c1[nH]c2ncccc2c1-c1nccc2cnccc12

InChI Key InChIKey=IIFABEVHKXGAPS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 331157   

TargetTGF-beta receptor type-1(Human)
Merck Patent

US Patent
LigandPNGBDBM331157(1-(1H-pyrrolo[2,3-b]pyridin-3-yl)-2,6-naphthyridin...)
Affinity DataIC50: 1.00E+3nMAssay Description:In-Vitro (Enzyme) Assay for Determination of the Efficacy of the Inhibitors of the Inhibition of TGF-Beta-Mediated EffectsAs an example, the ability ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent