BDBM331158 5-(1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)isoquinoline::US9725446, Compound A17

SMILES Cn1cc(-c2cccc3cnccc23)c2cccnc12

InChI Key InChIKey=VSJOEPNUQOKSEI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 331158   

TargetTGF-beta receptor type-1(Human)
Merck Patent

US Patent
LigandPNGBDBM331158(5-(1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)isoquino...)
Affinity DataIC50: 1.00E+3nMAssay Description:In-Vitro (Enzyme) Assay for Determination of the Efficacy of the Inhibitors of the Inhibition of TGF-Beta-Mediated EffectsAs an example, the ability ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent