BDBM331538 N-((S)-2-((3aS,6S,6aS)-6-chloro-3-oxotetrahydro-2H-furo[3,2-b]pyrrol-4(5H)-yl)-1-cyclohexyl-2-oxoethyl)-5-(pyridin-2-yl)thiophene-2-carboxamide::US9725459, 1

SMILES O[C@H]1CO[C@@H]2[C@@H](Cl)CN([C@H]12)C(=O)[C@@H](NC(=O)c1ccc(s1)-c1ccccn1)C1CCCCC1

InChI Key InChIKey=IDXQMTAKYJAPAU-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 331538   

TargetCathepsin K(Human)
Grunenthal

US Patent
LigandPNGBDBM331538(US9725459, 1 | N-((S)-2-((3aS,6S,6aS)-6-chloro-3-o...)
Affinity DataKi:  14nMAssay Description:Recombinant human cathepsins (CatS, CatK, CatL) were purchased from a Enzo Life Sciences. All assays were carried out in 96-well format using a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetCathepsin S(Human)
Grunenthal

US Patent
LigandPNGBDBM331538(US9725459, 1 | N-((S)-2-((3aS,6S,6aS)-6-chloro-3-o...)
Affinity DataKi:  402nMAssay Description:Recombinant human cathepsins (CatS, CatK, CatL) were purchased from a Enzo Life Sciences. All assays were carried out in 96-well format using a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent