BDBM331850 3-N-(3',5'-dimethylpiperazin-1-yl) 5'-fluoro lamotrigine::US10189859, Compound 119

SMILES C[C@H]1CN(C[C@@H](C)N1)c1nnc(c(N)n1)-c1cc(F)cc(Cl)c1Cl

InChI Key InChIKey=ADQIYYHQDQQCFT-OCAPTIKFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 331850   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Nektar Therapeutics

US Patent
LigandPNGBDBM331850(3-N-(3',5'-dimethylpiperazin-1-yl) 5'-fluoro lamot...)
Affinity DataIC50: <5.00E+4nMAssay Description:The potencies of the compounds provided herein to block specific Na+ channels was measured using automated patch clamp electrophysiologically of Nav1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Nektar Therapeutics

US Patent
LigandPNGBDBM331850(3-N-(3',5'-dimethylpiperazin-1-yl) 5'-fluoro lamot...)
Affinity DataIC50:  9.24E+4nMAssay Description:The potencies of the compounds provided herein to block specific Na+ channels was measured using automated patch clamp electrophysiologically of Nav1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent