BDBM332020 (R)- or (S)-6''- (1-(3-fluoro- 4-(trifluoro- methoxy) phenyl)ethyl)- 2-methyl- [4,4''- bipyrimidin]- 6(1H)-one::US10195201, Example 42::US10195201, Example 43

SMILES CC(c1ccc(c(F)c1)C(F)(F)F)c1cc(ncn1)-c1cc(=O)[nH]c(C)n1

InChI Key InChIKey=WNOJWVRBEGSAEM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 332020   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM332020((R)- or (S)-6''- (1-(3-fluoro- 4-(trifluoro- metho...)
Affinity DataKi:  7.5nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM332020((R)- or (S)-6''- (1-(3-fluoro- 4-(trifluoro- metho...)
Affinity DataKi:  45nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent