BDBM332550 5-chloroindol-2-yl 2-[(4-fluorophenyl)carbonyl]-2,7-diazaspiro[3.5]non-7-yl ketone::US10196369, Compound C5

SMILES CCc1c(N2CCN(C(=O)CNC(=O)c3ccccc3F)CC2)c(=O)n2nc(N3Cc4cnn(C)c4C3)nc2n1CC(=O)Nc1cc(C)cs1

InChI Key InChIKey=XPXHQTSYOPXLSN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332550   

TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Danatlas Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 332550BDBM332550(US20260015358, Example 263)
Affinity DataIC50: 100nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute, TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2026
Entry Details US Patent