BDBM332551 (2E)-3-(4-bromophenyl)-1-{2-[(4-chlorophenyl)methyl]-2,7-diazaspiro[3.5]non-7-yl}prop-2-en-1-one::US10196369, Compound C6

SMILES CCc1c(N2CCN(C(=O)C(=O)Nc3nccs3)CC2)c(=O)n2nc(N3CCN4C(=O)OC[C@H]4C3)nc2n1CC(=O)Nc1ccc(C(F)(F)F)cc1F

InChI Key InChIKey=DAPYGNHGWYASQC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332551   

TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Danatlas Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 332551BDBM332551(US20260015358, Example 264)
Affinity DataIC50: 100nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute, TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2026
Entry Details US Patent