BDBM33264 guanidine, 4

SMILES [#7]\[#6](-[#7])=[#7]\[#7]=[#6]-1-[#6](=O)-[#7]-c2ccccc-12

InChI Key InChIKey=OQLWRGUXLSZBEX-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 33264   

TargetSerine protease 1(Bos taurus (bovine))
University of Alabama At Birmingham

LigandPNGBDBM33264(guanidine, 4)
Affinity DataKi:  4.00E+3nM ΔG°:  -7.31kcal/molepH: 7.6 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University of Alabama At Birmingham

LigandPNGBDBM33264(guanidine, 4)
Affinity DataKi:  1.60E+4nM ΔG°:  -6.49kcal/molepH: 8.5 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E](Dengue virus 2 (strain TSV01))
University of Alabama At Birmingham

LigandPNGBDBM33264(guanidine, 4)
Affinity DataKi:  2.30E+4nM ΔG°:  -6.28kcal/molepH: 8.5 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed