BDBM33276 azo-sulfonamide, 2f

SMILES CN(CS([O-])(=O)=O)c1ccc(cc1)\N=N\c1cccc(c1)S(N)(=O)=O

InChI Key InChIKey=VFJFILTXOYUJNN-UHFFFAOYSA-M

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 33276   

TargetCarbonic anhydrase 12(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM33276(azo-sulfonamide, 2f)
Affinity DataKi:  7.40nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM33276(azo-sulfonamide, 2f)
Affinity DataKi:  63nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM33276(azo-sulfonamide, 2f)
Affinity DataKi:  109nMAssay Description:Inhibition of human cloned full length carbonic anhydrase 2 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM33276(azo-sulfonamide, 2f)
Affinity DataKi:  109nM ΔG°:  -9.49kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM33276(azo-sulfonamide, 2f)
Affinity DataKi:  2.44E+3nM ΔG°:  -7.65kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM33276(azo-sulfonamide, 2f)
Affinity DataKi:  7.40E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant carbonic anhydrase Rv3273 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM33276(azo-sulfonamide, 2f)
Affinity DataKi:  6.30E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant carbonic anhydrase Rv1284 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed