BDBM333397 2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazin-6-yl](cyclopropyl)amino}-1-(4-fluorophenyl)ethanol::US9730929, Example 18

SMILES OC(CN(C1CC1)c1ccc2ncc(-c3cc4ccccc4o3)n2n1)c1ccc(F)cc1

InChI Key InChIKey=HFKIIAOXQZOFPD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 333397   

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM333397(2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazin-6...)
Affinity DataIC50: 42nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
US Patent