BDBM335575 N-(3-(5-methyl-1,3,4-thiadiazol-2-yl)phenyl)-5-((4-(methylamino)piperidin-1-yl)methyl)pyrrolo[2,1-f][1,2,4]triazin-4-amine::US9737542, Example 18

SMILES CNC1CCN(Cc2ccn3ncnc(Nc4cccc(c4)-c4nnc(C)s4)c23)CC1

InChI Key InChIKey=QYSGIYQMNNEILM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 335575   

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 335575BDBM335575(US9737542, Example 18 | N-(3-(5-methyl-1,3,4-thiad...)
Affinity DataIC50: 550nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent