BDBM335835 6-[3-(5-Aminopyrazin-2-yl)-6- cyclobutyl-2-fluorophenoxy]pyridazin- 3-amine::US9732093, Compound 338

SMILES Nc1ccc(Oc2c(F)c(ccc2C2CCC2)-c2cnc(N)cn2)nn1

InChI Key InChIKey=ZLCUVUBNTLUTDA-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 335835   

TargetFlap endonuclease 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM335835(6-[3-(5-Aminopyrazin-2-yl)-6- cyclobutyl-2-fluorop...)
Affinity DataKi:  1.70nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent