BDBM336131 US9738658, Example 13

SMILES Cc1ncc(cn1)-n1ccc2cc(ccc12)N(CCO[Si](C)(C)C(C)(C)C)C(=O)c1c(Cl)ncnc1Cl

InChI Key InChIKey=OFNSWQVTKDARSV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336131   

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM336131(US9738658, Example 13)
Affinity DataIC50: 101nMAssay Description:For inhibition of triacylglycerol product formation, 11 uL reactions were run in white Polyplate-384 (PerkinElmer6007300) starting with a 30 minute p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent