BDBM336139 US9738658, Example 21

SMILES Cc1nnc(o1)-n1ccc2cc(ccc12)N(CCO[Si](C)(C)C(C)(C)C)C(=O)c1c(Cl)cccc1Cl

InChI Key InChIKey=UVKPDJZWQSUBAL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336139   

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM336139(US9738658, Example 21)
Affinity DataIC50: 16.3nMAssay Description:For inhibition of triacylglycerol product formation, 11 uL reactions were run in white Polyplate-384 (PerkinElmer6007300) starting with a 30 minute p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent