BDBM337573 US9745324, 42

SMILES CN1C[C@](C)(NC(=N)C(C)(C)S1(=O)=O)c1cc(Nc2nccc3cc(Br)cnc23)ccc1F

InChI Key InChIKey=JVHCXUWSWJCXPZ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337573   

TargetBeta-secretase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM337573(US9745324, 42)
Affinity DataKi:  18nMAssay Description:Reagents: Na+-Acetate pH 5.0; 1% Brij-35; Glycerol; Dimethyl Sulfoxide (DMSO); Recombinant human soluble BACE1 catalytic domain (>95% pure); APP Swed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent