BDBM338402 (3S,6R)-2-[[2-fluoro-4-[(3S,4R)-3- fluoro-4-(1,2,4-triazol-4-yl)-1- piperidyl]phenyl]methyl]-3-methyl- 6-phenyl-thiazinane 1,1-dioxide::US9751873, Example 90

SMILES C[C@H]1CC[C@H](c2ccccc2)S(=O)(=O)N1Cc1ccc(cc1F)N1CC[C@H]([C@@H](F)C1)n1cnnc1

InChI Key InChIKey=HIDIOJFYPYHFRA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 338402   

TargetNuclear receptor ROR-gamma(Human)
Genentech

US Patent
LigandPNGBDBM338402((3S,6R)-2-[[2-fluoro-4-[(3S,4R)-3- fluoro-4-(1,2,4...)
Affinity DataIC50: 18.5nMAssay Description:Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
US Patent