BDBM338882 US9751888, Compound 73::US9751888, Compound 83

SMILES C[C@H](NC(=O)c1c(N)nn2cccnc12)c1cc2cccc(Cl)c2c(=O)n1-c1ccccc1C

InChI Key InChIKey=JBCQPYWFSMKULR-HNNXBMFYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 338882   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Infinity Pharmaceuticals

US Patent
LigandPNGBDBM338882(US9751888, Compound 73 | US9751888, Compound 83)
Affinity DataIC50:  5.50E+3nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Homo sapiens (Human))
Infinity Pharmaceuticals

US Patent
LigandPNGBDBM338882(US9751888, Compound 73 | US9751888, Compound 83)
Affinity DataIC50:  300nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Infinity Pharmaceuticals

US Patent
LigandPNGBDBM338882(US9751888, Compound 73 | US9751888, Compound 83)
Affinity DataIC50:  750nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Infinity Pharmaceuticals

US Patent
LigandPNGBDBM338882(US9751888, Compound 73 | US9751888, Compound 83)
Affinity DataIC50:  5.50E+3nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Infinity Pharmaceuticals

US Patent
LigandPNGBDBM338882(US9751888, Compound 73 | US9751888, Compound 83)
Affinity DataIC50:  5.50E+3nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Homo sapiens (Human))
Infinity Pharmaceuticals

US Patent
LigandPNGBDBM338882(US9751888, Compound 73 | US9751888, Compound 83)
Affinity DataIC50:  5.50E+3nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Infinity Pharmaceuticals

US Patent
LigandPNGBDBM338882(US9751888, Compound 73 | US9751888, Compound 83)
Affinity DataIC50:  5.50E+3nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Infinity Pharmaceuticals

US Patent
LigandPNGBDBM338882(US9751888, Compound 73 | US9751888, Compound 83)
Affinity DataIC50:  300nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent