BDBM338944 US10201527, Compound 39::US10736881, Compound 39

SMILES CCn1cnc2cc(\C=C\C(=O)NO)ccc12

InChI Key InChIKey=QSXWWYTVHKKCFL-GQCTYLIASA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 338944   

TargetHistone deacetylase 1(Human)
Mei Pharma

US Patent
LigandPNGBDBM338944(US10201527, Compound 39 | US10736881, Compound 39)
Affinity DataIC50:  1.22E+3nMAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 8(Human)
Mei Pharma

US Patent
LigandPNGBDBM338944(US10201527, Compound 39 | US10736881, Compound 39)
Affinity DataIC50:  201nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 1(Human)
Mei Pharma

US Patent
LigandPNGBDBM338944(US10201527, Compound 39 | US10736881, Compound 39)
Affinity DataIC50:  1.22E+3nMAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 8(Human)
Mei Pharma

US Patent
LigandPNGBDBM338944(US10201527, Compound 39 | US10736881, Compound 39)
Affinity DataIC50:  201nMAssay Description:To determine EC50 where acetylated histone 3 was induced by 50%, Colo205 cells was cultivated in 96 well plate at 1.5×105 cells/well for 24 h. Colo20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent