BDBM339797 US10202340, Example 17

SMILES O[C@@H]([C@@H](CN1CCC1)NC(=O)CC1Cc2ccccc2C1)c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=SATQWNPLTDPCKA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 339797   

TargetCeramide glucosyltransferase(Human)
University of Michigan

US Patent
LigandPNGBDBM339797(US10202340, Example 17)
Affinity DataIC50: 24nMAssay Description:Inhibition of GlcCer production in whole wild-type MDCKII cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetCeramide glucosyltransferase(Human)
University of Michigan

US Patent
LigandPNGBDBM339797(US10202340, Example 17)
Affinity DataIC50: 41nMAssay Description:)Inhibition of GlcCer production in MDCKII cells stably expressing human MDR1 (obtained from The Netherlands Cancer Institute).More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetCeramide glucosyltransferase(Human)
University of Michigan

US Patent
LigandPNGBDBM339797(US10202340, Example 17)
Affinity DataIC50: 300nMAssay Description:Inhibition of GlcCer synthesis in broken wild-type MDCK cell preparationsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent