BDBM340491 US9763922, Example 22

SMILES CNC1=C(CN(CC1)C(C)=O)C(=N)Nc1cc(-c2cnn(C)c2)c(F)cc1F

InChI Key InChIKey=ZEQMHGLKDXEUCQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 340491   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 340491BDBM340491(US9763922, Example 22)
Affinity DataIC50: 20nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 340491BDBM340491(US9763922, Example 22)
Affinity DataIC50: 7.80E+3nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2019
Entry Details
US Patent