BDBM340495 US9763922, Example 26

SMILES CNC1=C(CN(CC1)C(C)=O)C(=N)Nc1ccc(F)c(-c2cnn(C)c2)c1F

InChI Key InChIKey=PLVSXVCWJRAMFP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 340495   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 340495BDBM340495(US9763922, Example 26)
Affinity DataIC50: 130nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 340495BDBM340495(US9763922, Example 26)
Affinity DataIC50: 1.46E+4nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2019
Entry Details
US Patent