BDBM341027 1-(5-Bromo-2-{[(3S)-3-[(4-cyclopentylpiperazin-1-yl)methyl]-3,4-dihydroisoquinolin-2(1H)-yl]carbonyl}phenyl)-N-(4-hydroxyphenyl)-N-(1H-indol-5-yl)-5-methyl-1H-pyrrole-3-carboxamide::US9765056, Example 80

SMILES Cc1cc(cn1-c1cc(Br)ccc1C(=O)N1Cc2ccccc2C[C@H]1CN1CCN(CC1)C1CCCC1)C(=O)N(c1ccc(O)cc1)c1ccc2[nH]ccc2c1

InChI Key InChIKey=RPSZDPUCOYVPSL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 341027   

TargetApoptosis regulator Bcl-2(Human)
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US Patent
LigandPNGBDBM341027(US9765056, Example 80 | 1-(5-Bromo-2-{[(3S)-3-[(4-...)
Affinity DataIC50: 6.80nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
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Date in BDB:
7/29/2019
Entry Details
US Patent