BDBM343341 (S)-4-(4-(difluoromethyl)-5-methylthiazol-2-yl)-N-(2-(3-fluoropyrrolidin-1-yl)-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-1-methyl-1H-pyrazole-5-carboxamide::US9777000, Example 4.23

SMILES Cc1sc(nc1C(F)F)-c1cnn(C)c1C(=O)Nc1ccn2nc(nc2c1)N1CC[C@H](F)C1

InChI Key InChIKey=VRIBONDAXOUERQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 343341   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Mochida Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 343341BDBM343341((S)-4-(4-(difluoromethyl)-5-methylthiazol-2-yl)-N-...)
Affinity DataIC50: 5nMAssay Description:IMAP TR-FRET Phosphodiersterase Evaluation Assay Kit (Molecular Device) was used for the measurement. Ten μL of a diluted test compound having e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent