BDBM345437 1-ethyl-4-[1-[4-(trifluoromethoxy)phenyl]sulfonyl-4,5-dihydroimidazol-2-yl]piperazine::US10202354, Example 102

SMILES CCN1CCN(CC1)C1=NCCN1S(=O)(=O)c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=MTPPHCGFIRRZAO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345437   

TargetLysine-specific demethylase 2B(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 345437BDBM345437(US10202354, Example 102 | 1-ethyl-4-[1-[4-(trifluo...)
Affinity DataIC50: 1.66nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent