BDBM345447 2-[[2-(4-ethylpiperazin-1-yl)-4,5-dihydroimidazol-1-yl]sulfonyl]benzonitrile::US10202354, Example 112

SMILES CCN1CCN(CC1)C1=NCCN1S(=O)(=O)c1ccccc1C#N

InChI Key InChIKey=BZFRKDRJLMMUHG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345447   

TargetLysine-specific demethylase 2B(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 345447BDBM345447(US10202354, Example 112 | 2-[[2-(4-ethylpiperazin-...)
Affinity DataIC50: 9.81nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent