BDBM345456 Propane-2-sulfonic acid [2-(2,5-dichloro-phenoxy)-6-(1,5-dimethyl-6-oxo-1,6-dihydro-pyridin-3-yl)-pyrimidin-4-yl]-amide::US10202360, Example 1

SMILES Cc1cc(-c2cc(NS(=O)(=O)C(C)C)nc(Oc3cc(Cl)ccc3Cl)n2)cn(C)c1=O

InChI Key InChIKey=QPOFQBNBLDDZCO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345456   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345456BDBM345456(US10202360, Example 1 | Propane-2-sulfonic acid [2...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent