BDBM345460 Propane-2-sulfonic acid [2-(2-chloro-5-methyl-phenoxy)-6-(1,5-dimethyl-6-oxo-1,6-dihydro-pyridin-3-yl)-pyrimidin-4-yl]-amide::US10202360, Example 5

SMILES Cc1ccc(Cl)c(Oc2nc(NS(=O)(=O)C(C)C)cc(-c3cc(C)c(=O)n(C)c3)n2)c1

InChI Key InChIKey=KCLXEDXIRGLKBK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345460   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345460BDBM345460(US10202360, Example 5 | Propane-2-sulfonic acid [2...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent