BDBM345505 Propane-2-sulfonic acid [6-(1- cyclobutylmethyl-5-methyl-6-oxo- 1,6-dihydro-pyridin-3-yl)-2-(2,4- difluoro-phenoxy)-pyrimidin-4-yl]- amide::US10202360, Example 50

SMILES CC(C)S(=O)(=O)Nc1cc(nc(Oc2ccc(F)cc2F)n1)-c1cc(C)c(=O)n(CC2CCC2)c1

InChI Key InChIKey=GLQTYBNBHPIZQZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345505   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345505BDBM345505(US10202360, Example 50 | Propane-2-sulfonic acid [...)
Affinity DataIC50: 5.00E+3nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent