BDBM345506 Acetic acid 2-{5-[2-(2,4-difluoro- phenoxy)-6-(propane-2- sulfonylamino)-pyrimidin-4-yl]-3- methyl-2-oxo-2H-pyridin-1-yl}- ethyl ester::US10202360, Example 51

SMILES CC(C)S(=O)(=O)Nc1cc(nc(Oc2ccc(F)cc2F)n1)-c1cc(C)c(=O)n(CCOC(C)=O)c1

InChI Key InChIKey=YPOLDCCXLISDMC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345506   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345506BDBM345506(US10202360, Example 51 | Acetic acid 2-{5-[2-(2,4-...)
Affinity DataIC50: 2.75E+3nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent