BDBM345507 Propane-2-sulfonic acid {2-(2,4- difluoro-phenoxy)-6-[5-methyl-6- oxo-1-(2,2,2-trifluoro-ethyl)-1,6- dihydro-pyridin-3-yl]-pyrimidin-4- yl}-amide::US10202360, Example 52

SMILES CC(C)S(=O)(=O)Nc1cc(nc(Oc2ccc(F)cc2F)n1)-c1cc(C)c(=O)n(CC(F)(F)F)c1

InChI Key InChIKey=NHOSGHWOLPSHRA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345507   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345507BDBM345507(US10202360, Example 52 | Propane-2-sulfonic acid {...)
Affinity DataIC50: 2.75E+3nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent