BDBM345510 Propane-1-sulfonic acid [2-(2,6- dimethyl-phenoxy)-6-(5-methyl-1- oxetan-3-yl-6-oxo-1,6-dihydro- pyridin-3-yl)-pyrimidin-4-yl]-amide::US10202360, Example 55

SMILES CCCS(=O)(=O)Nc1cc(nc(Oc2c(C)cccc2C)n1)-c1cc(C)c(=O)n(c1)C1COC1

InChI Key InChIKey=BPKARDAMHUSZFC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345510   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345510BDBM345510(US10202360, Example 55 | Propane-1-sulfonic acid [...)
Affinity DataIC50: 2.75E+3nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent