BDBM345518 N-(2-(2,4-difluorophenoxy)-6-(1,5- dimethyl-6-oxo-1,6-dihydropyridin- 3-yl)pyrimidin-4- yl)cyclopropanesulfonamide::US10202360, Example 63

SMILES Cc1cc(cn(C)c1=O)-c1cc(NS(=O)(=O)C2CC2)nc(Oc2ccc(F)cc2F)n1

InChI Key InChIKey=RUJINRFCZDQTHB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345518   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345518BDBM345518(US10202360, Example 63 | N-(2-(2,4-difluorophenoxy...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent