BDBM345536 N-(6-(1,5-dimethyl-6-oxo-1,6- dihydropyridin-3-yl)-2-(2,6- dimethylphenoxy)pyrimidin-4-yl)-3- fluoropropane-1-sulfonamide::US10202360, Example 81

SMILES Cc1cccc(C)c1Oc1nc(NS(=O)(=O)CCCF)cc(n1)-c1cc(C)c(=O)n(C)c1

InChI Key InChIKey=WEBCGLABSHXXND-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345536   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345536BDBM345536(US10202360, Example 81 | N-(6-(1,5-dimethyl-6-oxo-...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent