BDBM345543 N-(6-(1,5-dimethyl-6-oxo-1,6- dihydropyridin-3-yl)-2-((1,3,5- trimethyl-1H-pyrazol-4- yl)oxy)pyrimidin-4-yl)butane-1- sulfonamide::US10202360, Example 88

SMILES CCCCS(=O)(=O)Nc1cc(nc(Oc2c(C)nn(C)c2C)n1)-c1cc(C)c(=O)n(C)c1

InChI Key InChIKey=VVEPIKKBGHEBRT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345543   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345543BDBM345543(US10202360, Example 88 | N-(6-(1,5-dimethyl-6-oxo-...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent