BDBM345551 5-[2-(2,4-Difluoro-phenoxy)-6- ethanesulfonylmethyl-pyrimidin-4- yl]-1,3-dimethyl-1H-pyridin-2-one::US10202360, Example 96

SMILES CCS(=O)(=O)Cc1cc(nc(Oc2ccc(F)cc2F)n1)-c1cc(C)c(=O)n(C)c1

InChI Key InChIKey=NGAIMIKTLZJOCS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345551   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345551BDBM345551(US10202360, Example 96 | 5-[2-(2,4-Difluoro-phenox...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent