BDBM345552 Butane-1-sulfonic acid [2-(2,6- dimethyl-phenoxy)-6-(2-methyl-1- oxo-1,2-dihydro-isoquinolin-4-yl)- pyrimidin-4-yl]-amide::US10202360, Example 97

SMILES CCCCS(=O)(=O)Nc1cc(nc(Oc2c(C)cccc2C)n1)-c1cn(C)c(=O)c2ccccc12

InChI Key InChIKey=DYZIKIWKOCFWBE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345552   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345552BDBM345552(US10202360, Example 97 | Butane-1-sulfonic acid [2...)
Affinity DataIC50: 2.75E+3nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent