BDBM345640 Pentane-1-sulfonic acid [4-(1,5- dimethyl-6-oxo-1,6-dihydro-pyridin- 3-yl)-6-(2-fluoro-6-methyl- phenoxy)-[1,3,5]triazin-2-yl]-amide::US10202360, Example 185

SMILES CCCCCS(=O)(=O)Nc1nc(Oc2c(C)cccc2F)nc(n1)-c1cc(C)c(=O)n(C)c1

InChI Key InChIKey=KIJGVHJPRKPGDU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345640   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345640BDBM345640(US10202360, Example 185 | Pentane-1-sulfonic acid ...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent