BDBM345656 Propane-1-sulfonic acid [4- isopropoxy-6-(1-methyl-6-oxo-1,6- dihydro-pyridin-3-yl)-[1,3,5]triazin- 2-yl]-amide::US10202360, Example 201

SMILES CCCS(=O)(=O)Nc1nc(OC(C)C)nc(n1)-c1ccc(=O)n(C)c1

InChI Key InChIKey=MACYBESEIFWYLQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345656   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345656BDBM345656(US10202360, Example 201 | Propane-1-sulfonic acid ...)
Affinity DataIC50: 2.75E+3nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent