BDBM345674 (2R)-Pentane-2-sulfonic acid [2-(2- fluoro-6-methyl-phenoxy)-6-(1- methyl-6-oxo-1,6-dihydro-pyridin- 3-yl)-pyrimidin-4-yl]-amide::US10202360, Example 219

SMILES CCC[C@@H](C)S(=O)(=O)Nc1cc(nc(Oc2c(C)cccc2F)n1)-c1ccc(=O)n(C)c1

InChI Key InChIKey=AIQRITPUNJFXPU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345674   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345674BDBM345674(US10202360, Example 219 | (2R)-Pentane-2-sulfonic ...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent